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Vitamin C and Vitamin E for Healthy Aging

Two antioxidants that work as a team.

Quick answer

Vitamin C and vitamin E are the body's two main dietary antioxidants. Vitamin C is water-soluble and works in the fluids inside and around cells; vitamin E is fat-soluble and protects cell membranes. They work as a team: after vitamin E neutralizes a free radical, vitamin C helps recycle it so it can work again. Research has explored vitamin C in relation to post-meal glucose and oxidative stress, and vitamin E in relation to antioxidant status in people with blood sugar concerns. Adults need 75–90 mg of vitamin C and 15 mg of vitamin E daily; good sources are citrus, kiwi, peppers, almonds, sunflower seeds and spinach. Vitamin E may interact with blood thinners, so ask your doctor first if you take one.

Key takeaways

Vitamins C and E are among the best-known antioxidants. Together, they help protect cells from oxidative stress, which tends to rise with age and with blood sugar swings.

Vitamin C vs vitamin E

Vitamin CVitamin E
TypeWater-solubleFat-soluble
Where it worksFluids in and around cellsCell membranes
Adult daily need75 mg (women), 90 mg (men)15 mg
Upper limit2,000 mg1,000 mg
Best sourcesCitrus, kiwi, peppers, strawberriesAlmonds, sunflower seeds, spinach, oils

How they work as a team

Vitamin E sits in the fatty membranes around cells and stops chain reactions that damage fats. Once it has neutralized a free radical, vitamin C can restore it so it keeps working.

What research has explored

Vitamin C

Studies have looked at vitamin C and post-meal glucose, as well as oxidative stress markers in adults.

Vitamin E

Research has explored vitamin E's role in antioxidant status and cell protection in people with blood sugar concerns.

Why needs change with age

Getting both

Food comes first: a daily mix of colorful fruits, vegetables, nuts and seeds. Gluco Armor includes both vitamins alongside zinc, chromium, magnesium and biotin in one daily capsule.

Safety: vitamin E may increase bleeding risk with warfarin and other blood thinners. Ask your doctor before taking vitamin E supplements if you use one.

Sources

  1. NIH Office of Dietary Supplements – "Vitamin C" fact sheet.
  2. NIH Office of Dietary Supplements – "Vitamin E" fact sheet.
  3. Traber MG, Stevens JF. "Vitamins C and E: beneficial effects from a mechanistic perspective." Free Radical Biology & Medicine, 2011.

Common questions

Why take vitamins C and E together?

They work as a team; vitamin C helps recycle vitamin E.

How much vitamin C do adults need?

75 mg for women and 90 mg for men daily.

Is vitamin E safe with blood thinners?

It may increase bleeding risk, so ask your doctor first.

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